The human gastrointestinal tract or gut is naturally colonised by trillions of bacteria. These bacteria play an important role in human health, aiding digestion, metabolism and supporting the immune function. Collectively, these microorganisms are known as intestinal microbiota and they are essential to the normal function of the gut.
Gut dysbiosis occurs when the balance of good bacteria and bacteria in the gut is disrupted. This can be caused by many factors such as poor diet, alcohol consumption, poor dental hygiene, lack of sleep, stress, antibiotic use and even disease. Once the gut microbiota is altered, pathogenic bacteria such as E. coli may over colonise the gut and release toxic by-product known as lipopolysaccharide (LPS) or endotoxins.
Increasing scientific evidence suggests that LPS is a potent activator of inflammatory responses in the body. Inflammation has been linked to many intestinal conditions including Inflammatory Bowel Disease (IDB) as well as organ dysfunctions such as the liver.